Title

The Multi-Mode Modulator: A Versatile Fluidic Device for Two-Dimensional Gas Chromatography

Document Type

Article

Publication Date

2-9-2018

Publication Title

Journal of Chromatography A

Abstract

A fluidic device called the multi-mode modulator (MMM) has been developed for use as a comprehensive two-dimensional gas chromatography (GC x GC) modulator. The MMM can be employed in a wide range of capacities including as a traditional heart-cutting device, a low duty cycle GC x GC modulator, and a full transfer GC x GC modulator. The MMM is capable of producing narrow component pulses (widths <50 ms) while operating at flows compatible with high resolution chromatography. The sample path of modulated components is confined to the interior of a joining capillary. The joining capillary dimensions and the position of the columns within the joining capillary can be optimized for the selected modulation mode. Furthermore, the joining capillary can be replaced easily and inexpensively if it becomes fouled due to sample matrix components or column bleed. The principles of operation of the MMM are described and its efficacy is demonstrated as a heart-cutting device and as a GC x GC modulator.

Volume

1536

Issue

1

First Page

6

Last Page

15

DOI

https://doi.org/10.1016/j.chroma.2017.06.030

ISSN

0021-9673

Comments

ESSN: 1873-3778

Rights

Elsevier

Link to Full Text

Share

COinS