Title

Single drop microextraction — Development, applications and future trends

Document Type

Article

Publication Date

4-16-2010

Publication Title

Journal of Chromatography A

Abstract

Single drop microextraction (SDME) has emerged over the last 10-15 years as one of the simplest and most easily implemented forms of micro-scale sample cleanup and preconcentration. In the most common arrangement, an ordinary chromatography syringe is used to suspend microliter quantities of extracting solvent either directly immersed in the sample, or in the headspace above the sample. The same syringe is then used to introduce the solvent and extracted analytes into the chromatography system for identification and/or quantitation. This review article summarizes the historical development and various modes of the technique, some theoretical and practical aspects, recent trends and selected applications.

Volume

1217

Issue

16

First Page

2326

Last Page

2336

DOI

https://doi.org/10.1016/j.chroma.2009.10.089

ISSN

0021-9673

Comments

ESSN: 1873-3778

Rights

© 2009 Elsevier B.V.

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